![]() If you no longer wish to have this DailyMed RSS service, simply delete the copied URL from your RSS Reader.Product Summary This product requires a valid prescription for shipment, please note that may not accept prescriptions faxed or emailed by patients. To view updated drug label links, paste the RSS feed address (URL) shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X. What will I get with the DailyMed RSS feed?ĭailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed.ĭailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. To receive all DailyMed Updates for the last seven days Reddy's Laboratories Louisiana, LLCĬopy the URL below and paste it into your RSS Reader application. Reddy's Laboratories Louisiana, LLC (830397282)ĭr. SILVER SULFADIAZINE (UNII: W46JY43EJR) (SILVER SULFADIAZINE - UNII:W46JY43EJR) The drug should not be withdrawn from the therapeutic regimen while there remains the possibility of infection except if a significant adverse reaction occurs. Treatment with Silver Sulfadiazine Cream should be continued until satisfactory healing has occurred or until the burn site is ready for grafting. However, if individual patient requirements make dressings necessary, they may be used. Administration may be accomplished in minimal time because dressings are not required. Whenever necessary, the cream should be reapplied to any areas from which it has been removed due to patient activity. The cream should be applied once to twice daily to a thickness of approximately 1/16 inch. The burn areas should be covered with Silver Sulfadiazine Cream at all times. The burn wounds are then cleansed and debrided and Silver Sulfadiazine Cream is applied under sterile conditions. Prompt institution of appropriate regimens for care of the burned patient is of prime importance and includes the control of shock and pain. Some of the reactions which have been associated with sulfonamides are as follows: blood dyscrasias, including agranulocytosis, aplastic anemia, thrombocytopenia, leucopenia and hemolytic anemia, dermatologic and and allergic reactions, including Stevens-Johnson syndrome and exfoliative dermatitis, gastrointestinal reactions, hepatitis and hepatocellular necrosis, CNS reactions, and toxic nephrosis.įOR TOPICAL USE ONLY - NOT FOR OPHTHALMIC USE: Although few have been reported, it is possible that any adverse reaction associated with sulfonamides may occur. However, reduction in bacterial colonization has caused delayed separation, in some cases necessitating escharotomy in order to prevent contracture.Ībsorption of silver sulfadiazine varies depending upon the percent of body surface area and the extent of the tissue damage. Reduction in bacterial growth after application of topical antibacterial agents has been reported to permit spontaneous healing of deep partial thickness burns by preventing conversion of the partial thickness to full thickness by sepsis. Other infrequently occurring events include skin necrosis, erythema multiforme, skin discoloration, burning sensation, rashes, and interstitial nephritis. A higher incidence has been seen in patients treated concurrently with cimetidine. ![]() The incidence of leukopenia in various reports averages about 20%. Recovery is not influenced by continuation of silver sulfadiazine therapy. ![]() Rebound to normal leukocyte levels follows onset within two to three days. Maximal white blood cell depression occurs within two to four days of initiation of therapy. Leukopenia associated with silver sulfadiazine administration is primarily characterized by decreased neutrophil count. Several cases of transient leukopenia have been reported in patients receiving silver sulfadiazine therapy. ![]()
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